Jack Hammond


Jack Hammond-page-001

Jack grew up in northern New York and received a B.A. in biology from Ithaca College in Ithaca, New York. Following graduation, he worked in a microbiology lab at Dartmouth College in Hanover New Hampshire as a research assistant. Jack enrolled in the Molecular and Cellular Biology Graduate Program at Dartmouth in 2010, where he studied the role of an oxygen-sensitive transcription factor on expression of virulence-associated processes in the opportunistic pathogen Pseudomonas aeruginosa. He received his PhD from the Geisel School of Medicine at Dartmouth in 2017.

Jack’s work in the Stephanopoulos lab is focused on engineering the oleaginous yeast Yarrowia lipolytica for robust growth and abundant lipid production when organic acids are supplied as a primary carbon source. These engineered yeasts will be applied as part of a larger initiative focused on bioprocessing of various waste streams.

Jack lives the life of a typical postdoc, enjoying running, reading, or watching TV and eating in his spare time.

Email: jmhh (at) mit (dot) edu



Hammond, JH., et al. 2016. Environmentally endemic Pseudomonas aeruginosa strains with mutations in lasR are associated with increased disease severity in corneal ulcers. mSphere. 10.1128/mSphere.00140-6

Hammond, JH., Dolben, EF., Smith, TJ., Hogan, DA. 2015. Links between Anr and quorum sensing in Pseudomonas aeruginosa biofilms. J. Bacteriol. 197(17): 2810-2820

Tan, J., Hammond, JH., Hogan, DA., Greene, CS. 2015. ADAGE: Integration of publically available Pseudomonas aeruginosa gene expression data with denoising autoencoders illuminates microbe-host interactions. mSystems. 10.1128/mSystems.00025-15

Koeppen, K., Hampton, TH., Jarek, M., Scharfe, M., Gerber, SA., Mielcarz, DW., Demers, EG., Dolben, EL., Hammond, JH., Hogan, DA., Stanton, BA. 2016. A novel mechanism of host-pathogen interaction through sRNA in bacterial outer membrane vesicles. PLoS Pathog. 12(6): e1005672

Jackson, AA., Daniels, EF., Hammond, JH., Willger, SD., Hogan, DA. 2014. Global regulator Anr represses PlcH phospholipase activity in Pseudomonas aeruginosa when oxygen is limiting. Microbiology. 160(10): 2215-2225

Hogan, DA., Hammond, JH. 2013. Bacterial type 6 secreted phospholipases play family feud. Cell Host Microbe. 13(5): 507-508

Jackson, AJ., Gross, MJ., Daniels, EF., Hampton, TH., Hammond, JH., Vallet-Gely, I., Dove, SL., Stanton, BA., Hogan, DA. 2013. Anr and its activation by PlcH activity in Pseudomonas aeruginosa host colonization and virulence. J. Bacteriol. 195(13): 3093-3104

Zegans, ME., Wozniak, D., Griffin, E., Toutain-Kidd, CM., Hammond, JH., Garfoot, A., Lam, JS. 2012. Pseudomonas aeruginosa exopolysaccharide Psl promotes resistance to the biofilm inhibitor polysorbate 80. Antimicrob Agents Chemother. 56(8): 4112-4122

Kabeche, R., Baldissard, S., Hammond, JH., Howard, L.Moseley, JB. 2011. The filament-forming protein Pil1 assembles linear eisosomes in fission yeast. Mol Biol Cell. 22(21): 4059-4067

Cady, KC., White, AS., Hammond, JH., Abendroth, MD., Karthikeyan, RS., Lalitha, P., Zegans, ME., O’Toole, GA. 2011. Prevalence, conservation and functional analysis of Yersinia and Escherichia CRISPR regions in clinical Pseudomonas aeruginosa isolates. Microbiology. 157(2): 430-437

Kuchma, SL., Ballok, AE., Merritt, JH., Hammond, JH., Lu, W., Rabinowitz, JD., O’Toole, GA. 2010. Cyclic-di-GMP-mediated repression of swarming motility by Pseudomonas aeruginosa: the pilY1 gene and its impact on surface-associated behaviors. J Bacteriol. 192(12): 2950-2964

Khan, W., Bernier, SP., Kuchma, SL., Hammond, JH., Hasan, F., O’Toole, GA. 2010. Aminoglycoside resistance of Pseudomonas aeruginosa biofilms modulated by extracellular polysaccharide. Int Microbiol. 13(4): 207-212

Zegans, ME., Wagner, JC., Cady, KC., Murphy, DM., Hammond, JH., O’Toole, GA. 2009. Interaction between bacteriophage DMS3 and host CRISPR region inhibits group behaviors of Pseudomonas aeruginosa. J. Bacteriol. 191(1): 210-219