Publications 2016

2019 | 2018 | 2017 | 2016 | 2015 | 2014 | 2013

2016

C. Berrios, M. Padi, M. A. Keibler, D. E. Park, V. Molla, J. Cheng, S. M. Lee, G. Stephanopoulos, J. Quackenbush, and J. A. DeCaprio, “Merkel Cell Polyomavirus Small T Antigen Promotes Pro-Glycolytic Metabolic Perturbations Required for Transformation,” PLoS Pathog., 12 (11), 1–21, 2016.
10.1371/journal.ppat.1006020

N. Liu, K. Qiao, and G. Stephanopoulos, “13C Metabolic Flux Analysis of acetate conversion to lipids by Yarrowia lipolytica,” Metab. Eng., 38, 86–97, 2016.
10.1016/j.ymben.2016.06.006

P. Xu, K. Qiao, W. S. Ahn, and G. Stephanopoulos, “Engineering Yarrowia lipolytica as a platform for synthesis of drop-in transportation fuels and oleochemicals.,” Proc. Natl. Acad. Sci. U. S. A., 113 (39), 10848–53, 2016.
10.1073/pnas.1607295113

M. A. Keibler, T. M. Wasylenko, J. K. Kelleher, O. Iliopoulos, M. G. Vander Heiden, and G. Stephanopoulos, “Metabolic requirements for cancer cell proliferation,” Cancer Metab., 4 (1), 16, 2016.
10.1186/s40170-016-0156-6

A. J. Shaw, F. H. Lam, M. Hamilton, A. Consiglio, K. MacEwen, E. E. Brevnova, E. Greenhagen, W. G. LaTouf, C. R. South, H. van Dijken, G. Stephanopoulos, “Metabolic engineering of microbial competitive advantage for industrial fermentation processes,” Science, 353 (6299), 583-586, 2016.
10.1126/science.aaf6159

C. Zhang, X. Chen, G. Stephanopoulos, and H. P. Too, “Efflux transporter engineering markedly improves amorphadiene production in Escherichia coli,” Biotechnol. Bioeng., 113 (8), 1755–1763, 2016.
10.1002/bit.25943

H. Zhang and G. Stephanopoulos, “Co-culture engineering for microbial biosynthesis of 3-amino-benzoic acid in Escherichia coli,” Biotechnol. J., 11 (7), 981–987, 2016.
10.1002/biot.201600013

Z. J. Li, K. Qiao, W. Shi, B. Pereira, H. Zhang, B. D. Olsen, and G. Stephanopoulos, “Biosynthesis of poly(glycolate-co-lactate-co-3-hydroxybutyrate) from glucose by metabolically engineered Escherichia coli,” Metab. Eng., 35, 1–8, 2016.
10.1016/j.ymben.2016.01.004

A. M. Silverman, K. Qiao, P. Xu, and G. Stephanopoulos, “Functional overexpression and characterization of lipogenesis-related genes in the oleaginous yeast Yarrowia lipolytica,” Appl. Microbiol. Biotechnol., 100 (8), 3781–3798, 2016.
10.1007/s00253-016-7376-0

W. Biggs, C. Giaw, K. Sagliani, S. Shankar, and G. Stephanopoulos, “Overcoming heterologous protein interdependency to optimize P450-mediated Taxol precursor synthesis in Escherichia coli,” Proc. Natl. Acad. Sci., 113 (12), 3209–3214, 2016.
10.1073/pnas.1515826113

F. Cheng, Q. Gong, H. Yu, and G. Stephanopoulos, “High-titer biosynthesis of hyaluronic acid by recombinant Corynebacterium glutamicum,” Biotechnol. J., 11, 574-584, 2016.
10.1002/biot.201500404

B. Pereira, Z. J. Li, M. De Mey, C. G. Lim, H. Zhang, C. Hoeltgen, and G. Stephanopoulos, “Efficient utilization of pentoses for bioproduction of the renewable two-carbon compounds ethylene glycol and glycolate,” Metab. Eng., 34, 80–87, 2016.
10.1016/j.ymben.2015.12.004

J. R. King, S. Edgar, K. Qiao, and G. Stephanopoulos,”Accessing nature’s diversity through metabolic engineering and synthetic biology,” F1000Research, 5, 397-407, 2016.
10.12688/f1000research.7311.1

S. Edgar, K. Zhou, K. Qiao, J. R. King, J. H. Simpson, and G. Stephanopoulos, “Mechanistic Insights into Taxadiene Epoxidation by Taxadiene-5α-Hydroxylase,” ACS Chem. Biol., 11, 460-469, 2016.
10.1021/acschembio.5b00767

B. Pereira, H. Zhang, M. De Mey, C. G. Lim, Z. J. Li, and G. Stephanopoulos, “Engineering a novel biosynthetic pathway in Escherichia coli for production of renewable ethylene glycol,” Biotechnol. Bioeng., 113 (2), 376–383, 2016.
10.1002/bit.25717

J. Friedlander, V. Tsakraklides, A. Kamineni, E. H. Greenhagen, A. L. Consiglio, K. MacEwen, D. V. Crabtree, J. Afshar, R. L. Nugent, M. A. Hamilton, A. Joe Shaw, C. R. South, G. Stephanopoulos, and E. E. Brevnova, “Engineering of a high lipid producing Yarrowia lipolytica strain,” Biotechnol. Biofuels, 9 (1), 77-88, 2016.
10.1186/s13068-016-0492-3