Growing up in Taiyuan, Shanxi (China), Wentao obtained his bachelor’s degrees in chemical engineering and chemistry from University of Wisconsin – Madison. As an undergraduate researcher, he studied on stem cell tissue engineering in Professor Sean Palecek’s Lab. Wentao received his master’s degree in chemical engineering here at MIT. During his undergraduate and graduate studies, Wentao worked as co-op engineers at Cummins, Corning and FDA. In his spare time, Wentao likes to play tennis and travel for fun. Wentao’s PhD research projects are centered on cancer and diabetes metabolism.
Both cancer and type-2 diabetes are top 10 leading causes of death in the US. Research into the metabolic aspects of these diseases is crucial for the development of their therapies. Through genetic modifications of cells and metabolic analyses using stable isotopic tracers and flux simulations, the perplexing nature of rewired metabolic networks in these diseases can be elucidated. Such insights provide a more global mechanistic view of the diseases as well as a guidance to formulate therapeutic strategies.
Email: dwt (at) mit (dot) edu
Dong, W., Keibler, M. A., Stephanopoulos, G. Review of metabolic pathways activated in cancer cells as determined through isotopic labeling and network analysis. Metabolic Engineering 43, 2017. doi: 10.1016/j.ymben.2017.02.002.
Lian, X., Bao, X., Al-Ahmad, A., Liu, J., Wu, Y., Dong, W., Dunn, K. K., Shusta, E. V., Plalecek, S. P. Efficient angioblasts derivation from human pluripotent stem cells via small-molecule activation of Wnt signaling. Stem Cell Reports, 3(5), 804-816, 2014. doi: 10.1016/j.stemcr.2014.09.005.